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BCL3 — MDM2

Text-mined interactions from Literome

DeHaan et al., Cancer Chemother Pharmacol 2001 : In the ovarian carcinoma cell line A2780, cisplatin was shown to induce expression of p21WAF1, Gadd45 and Mdm2, but cisplatin had no effect on expression of Bax, Bcl-2, Bcl-x1 , or Cyclin G. Inhibition of cisplatin induced ERK activity by PD98059 resulted in decreased levels of p21WAF1, Gadd45 and Mdm2
Kashatus et al., Genes Dev 2006 : Experiments presented here indicate that Bcl-3 is inducible by DNA damage and is required for the induction of Hdm2 gene expression and the suppression of persistent p53 activity