Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MGP

Text-mined interactions from Literome

Julien et al., Endocrinology 2007 (MAP Kinase Signaling System) : Finally, a specific ERK1/2 inhibitor, UO126, blocks Pi-stimulated MGP expression in ATDC5 cells, indicating that ERK1/2 mediates, mainly, the effects of Pi
Suttamanatwong et al., J Cell Biochem 2007 : However, phorbol 12-myristate 13-acetate ( PMA ), a selective PKC activator induced MGP mRNA expression through activation of extracellular signal regulated kinase ( ERK )
Julien et al., J Bone Miner Res 2009 : U0126 ( MEK1/2 inhibitor ) suppressed Pi-stimulated MGP and Fra-1 expression, indicating that ERK1/2 is required for Pi-dependent regulation of MGP and Fra-1