Gene interactions and pathways from curated databases and text-mining

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ICAM1 — MMP14

Text-mined interactions from Literome

Lee et al., J Allergy Clin Immunol 2003 (Asthma...) : An aim of this study was to evaluate the effect of MMP inhibitors on the expression of ICAM-1 and VCAM-1 in the migration of inflammatory cells in a murine model of TDI induced asthma ... We used a murine model to investigate TDI induced asthma to examine the possible involvement of ICAM-1 and VCAM-1 in the pathogenesis of that disease and the effect of MMP inhibitors on the expression of ICAM-1 and VCAM-1 ... These results suggest that MMP inhibitors regulate inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression and possibly also by suppressing IL-1beta, IL-4, and TNF-alpha expression
Matías-Román et al., Blood 2005 : Binding of monocytes to TNF-alpha activated human endothelial cells as well as to VCAM-1 or ICAM-1 also resulted in an increase of MT1-MMP expression
Sithu et al., J Biol Chem 2007 : MT1-MMP mediated the ectodomain cleavage of ICAM-1 that was blocked by TIMP-2 and -3