Gene interactions and pathways from curated databases and text-mining

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FOS — MMP16

Text-mined interactions from Literome

Westermarck et al., FASEB J 1999 (Neoplasm Invasiveness...) : This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the role of mitogen activated protein kinases and AP-1 and ETS transcription factors in the regulation of MMP gene expression during invasion process
Kajanne et al., J Cell Physiol 2007 : Here we provide genetic and biochemical evidence that EGF-R- and AP-1 mediated signals are required for MMP expression and collagen contraction in fibroblasts
Oliver et al., J Rheumatol 2007 (Arthritis, Experimental...) : We evaluated whether a vanadium AP-1 inhibitor could reduce MMP expression and subsequent joint damage in CIA
Hasegawa et al., Exp Cell Res 2009 (Neoplasm Invasiveness) : To assess the role of AP-1 function, we examined the effects of dominant negative Fos ( DeltaFos ), BATF and siRNA against c-Jun on MMP production in v-Crk transformed cells which have augmented production of MMP-2 and MMP-9