Gene interactions and pathways from curated databases and text-mining

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MMP21 — MYLIP

Text-mined interactions from Literome

Stanczyk et al., Arthritis Rheum 2011 (Arthritis, Rheumatoid...) : Previously, we described increased expression of miR-155 and miR-146a in rheumatoid arthritis ( RA ) and showed a repressive effect of miR-155 on matrix metalloproteinase ( MMP ) expression in RA synovial fibroblasts ( RASFs )
Chiang et al., Biochim Biophys Acta 2013 (Breast Neoplasms...) : Anti-miR-182 increased the MMP inhibitor RECK protein in MDA-MB-231 cells while pre-miR-182 reduced RECK protein but not mRNA in normal mammary epithelial H184B5F5/M10 cells
Guo et al., Oncol Rep 2013 : Furthermore, the overexpression of miR-708 reduced the expression of Akt1, CCND1, MMP2 , EZH2, Parp-1 and Bcl2 in A172 and T98G cells
Lin et al., Br J Cancer 2013 (Lung Neoplasms...) : Anti-miR-92a attenuates MMP activity, migration and invasion of H1299 cells and STAT3 overexpressing H460 cells, suggesting miR-92a is critical for STAT3 induced invasiveness.Conclusion : The STAT3 induced miR-92a promotes cancer invasion by suppressing RECK and targeting of the STAT3/miR-92a axis may be helpful for cancer treatment
Jin et al., Asian Pac J Cancer Prev 2013 (Bone Neoplasms...) : This was confirmed by western blotting, which showed that miR-218 expression inhibited TIAM1, MMP2 and MMP9 protein expression