Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Makeyev et al., Mol Cell 2007 (Neuroblastoma) : The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
Lee et al., Biochem Biophys Res Commun 2008 : Using loss-of function and gain-of function approaches, we demonstrate that functional miR-302b is necessary to maintain stem cell self-renewal and inhibit neuronal differentiation of human ECCs
Le et al., Mol Cell Biol 2009 : Pathway analysis suggests that a subset of miR-125b repressed targets antagonizes neuronal genes in several neurogenic pathways, thereby mediating the positive effect of miR-125b on neuronal differentiation ... Together, we report here for the first time the important role of miR-125b in human neuronal differentiation
Aranha et al., PloS one 2011 : Our results provide new insight into the molecular mechanisms by which miR-34a modulates neural differentiation, suggesting that miR-34a is required for proper neuronal differentiation , in part, by targeting SIRT1 and modulating p53 activity
Dill et al., Genes Dev 2012 : Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2
Hamada et al., Neurochem Int 2012 : Overexpression of miR-221 induced neuronal differentiation of PC12 cells in the absence of NGF treatment, and also enhanced neuronal differentiation caused by low-dose NGF
Tan et al., Genes Cells 2012 : Over-expression of miR-9 negatively regulates the Hes1 protein expression by interacting with the 3'-UTR of Hes1 mRNA, thereby inducing cell cycle exit and neuronal differentiation