Gene interactions and pathways from curated databases and text-mining

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BCL9 — NGF

Text-mined interactions from Literome

Bui et al., J Cell Biol 2001 : We investigated the effect of NGF on the expression of Bcl-xL , an anti-apoptotic Bcl-2 family protein ... NGF induced NFkappaB activity and Bcl-xL expression were inhibited in cells overexpressing the NFkappaB inhibitor, IkappaBalpha
Bui et al., J Neurochem 2002 (Pheochromocytoma) : We have previously shown that nerve growth factor (NGF) induced activation of nuclear factor-kappaB increased neuronal expression of Bcl-xL , an anti-apoptotic Bcl-2 family protein ... Treatment of hippocampal neurones with the blocking anti-p75 antibody inhibited constitutive and NGF induced Bcl-xL expression, activation of Akt, and blocked the protective effect of NGF against excitotoxic and apoptotic injury