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PPARG — STAT1
Text-mined interactions from Literome
Stephens et al., Biochem Biophys Res Commun 1999
:
PPARgamma ligand dependent
induction of
STAT1 , STAT5A, and STAT5B during adipogenesis
Hogan et al., Biochem Biophys Res Commun 2001
:
LIF, a potent activator of STAT3 and a weak activator of STAT 1 in these cells, resulted in some binding to the IFNgamma responsive element in the
PPARgamma2 promoter that was
mediated by
STAT 1
Rhee et al., Mol Cell Endocrinol 2008
:
Either PD98059, an ERK inhibitor or fludarabine, a
STAT1 inhibitor
restored leptin inhibited
PPARgamma expression and subsequent lipid accumulation, but inhibitors for PI-3K ( LY294002 ) and for STAT3 ( piceatannol ) did not