Gene interactions and pathways from curated databases and text-mining

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BCL6 — PTGS2

Text-mined interactions from Literome

Tari et al., Lab Invest 2005 (Breast Neoplasms) : However, we did not observe any changes in Bcl-2, Bcl-XL , or Bax expression induced by COX-2 or PGE2
Liu et al., Ann Hematol 2007 (Leukemia) : Taken together, our results demonstrate for the first time that downregulation of cyclooxygenase-2 expression, disruption of mitochondrial membrane potential, activation of caspase-3, downregulation of Bcl-2, Bcl-Xl , and Mcl-1, and upregulation of Bax are involved in PPAR-gamma agonists induced apoptosis in these two human monocyte leukemia cells
Chen et al., Clin Cancer Res 2010 (Carcinoma, Hepatocellular...) : Furthermore, using the shRNA and transgene coexpression adenovirus system, we showed that silencing of COX-2 increased the sensitivity of hepatocellular carcinoma to TRAIL through inhibition of Bcl-2 and Bcl-w