Gene interactions and pathways from curated databases and text-mining

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RUNX2 — VEGFA

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Zelzer et al., Mech Dev 2001 : Finally, over-expression of Cbfa1 in fibroblasts induces an increase in their VEGF mRNA level and protein production by stimulating VEGF transcription
Ter Elst et al., Cancer Res 2011 (Leukemia, Myeloid, Acute...) : Repression of vascular endothelial growth factor expression by the runt related transcription factor 1 in acute myeloid leukemia
Kwon et al., J Cell Biochem 2011 : Physical and functional interactions between Runx2 and HIF-1a induce vascular endothelial growth factor gene expression
Lee et al., J Biol Chem 2012 : Furthermore, overexpression of Runx2 resulted in the significant enhancement of vascular endothelial growth factor ( VEGF ) promoter reporter activity and protein secretion