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RELA — S100P

Text-mined interactions from Literome

Arumugam et al., J Natl Cancer Inst 2006 (Neoplasm Invasiveness...) : In vitro, cromolyn ( 100 microM ) inhibited S100P stimulated Panc-1 cell proliferation ( S100P, mean = 0.93 U, versus S100P + cromolyn, mean = 0.56 U, difference = 0.37 U ; 95 % confidence interval [ CI ] = 0.24 to 0.49 U ; P = .001, n = 3 ), invasion ( S100P, mean = 58.0 %, versus S100P + cromolyn, mean = 9.4 %, difference = 48.6 % ; 95 % CI = 38.8 % to 58.8 % ; P < .001, n = 3 ), and NFkappaB activity ( S100P, mean = 14,460, versus S100P + cromolyn, mean = 7360 photons/s, difference = 7100 photons/s ; 95 % CI = 3689 to 10 510 photons/s ; P = .005, n = 3 )
Fuentes et al., Dis Colon Rectum 2007 (Adenocarcinoma...) : These data indicate that S100P is expressed at greater levels in colon cancer than matched normal tissue and that S100P stimulates colon cancer cell growth, migration, Erk phosphorylation, and NFkappaB activation in vitro, suggesting that this ligand/receptor pair may be targeted for the development of new therapies