Gene interactions and pathways from curated databases and text-mining

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RELA — SIRT6

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Stein et al., Aging 2010 (Atherosclerosis...) : However, SIRT1 prevented endothelial superoxide production, inhibited NF-kappaB signaling, and diminished expression of adhesion molecules
Lim et al., Biol Reprod 2013 (Inflammation...) : To determine whether SIRT6 affects NFKB transcriptional activity, primary amnion cells were transfected with NFKB tagged with luciferase and stimulated with IL1B