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SNAP25 — VEGFA
Text-mined interactions from Literome
Kimura et al., Biochem Biophys Res Commun 2002
:
SNAP , GSNO, NOC18, and NOR4
enhanced the
VEGF reporter activity under normoxia and modulated the hypoxic induction
Chin et al., Oncogene 1997
(Carcinoma, Hepatocellular...) :
SNAP at 0.5 mM induced maximal stimulation of 4.4 and 3.7 kb
VEGF mRNA expression after 6 h about 11 and 8 fold increase, respectively above
control level ... To evaluate the
effect of
SNAP on
VEGF mRNA stability, half-lives of VEGF mRNA were measured in A-172 cells cultured with or without 0.5 mM SNAP and treated with actinomycin D ( 25 microg/ml ) ...
VEGF expression
induced by
SNAP was inhibited by guanylate cyclase inhibitors, methylene blue ( 10 microM ) and LY-83583 ( 1 microM ), and by the protein synthesis inhibitor, cycloheximide ( 25 microg/ml )