Gene interactions and pathways from curated databases and text-mining

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IL8 — SYK

Text-mined interactions from Literome

Wang et al., J Immunol 2006 : ICAM-1 engagement by HRV and cross linking Abs also induced phosphorylation of p38 in a Syk dependent manner, and conversely, knockdown of Syk by short interfering ( si ) RNA substantially diminished p38 activation and IL-8 gene expression
Lau et al., J Immunol 2008 : We recently demonstrated the Syk tyrosine kinase to be an important mediator of HRV-ICAM-1 signaling : Syk regulates replication independent p38 MAPK activation and IL-8 expression