Brucet et al., Genes Immun 2004
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Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1 ... These results indicate that both STAT1 and IRF-1 are required for the IFN-gamma induction of Tap-1 and Lmp-2 genes
White et al., Immunity 1996
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Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice ... The role of IRF-1 in the regulation of TAP1 and LMP2 suggests a mechanism for the antiviral properties of IRF-1 and the unexpected deficiency of CD8+ T cells observed in IRF-1-/- mice
Penninger et al., Immunity 1997
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The absence of IRF-1 resulted in decreased expression of LMP2, TAP1 , and MHC class I on thymic stromal cells