Gene interactions and pathways from curated databases and text-mining

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CXCL12 — TCF25

Text-mined interactions from Literome

Lee et al., Mol Cancer Res 2004 (Breast Neoplasms...) : Stromal cell derived factor 1alpha ( SDF-1alpha ; CXCL12 ) stimulation of breast cancer cells resulted in phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and activation of the FKHRL1 transcription factor
Luo et al., Neurosci Lett 2006 : Here, we report that SDF1alpha/CXCR4 signaling activates beta-catenin/TCF transcriptional activity in embryonic rat spinal cord neural progenitors ... Concomitant with beta-catenin accumulation in the cytoplasm, SDF1alpha enhanced nuclear translocation of beta-catenin and its binding to nuclear transcription factor T cell-specific transcription factor/lymphoid enhancer binding factor ( TCF/LEF )
Hamdan et al., Mol Cancer Res 2011 : Chromatin immunoprecipitation showed that the ELK-1 transcription factor binds to the pdgf-b promoter in response to SDF-1a