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PRKAB1 — TMED7
Text-mined interactions from Literome
Kayampilly et al., Endocrinology 2009
:
The chemical activator of
AMPK ( 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, 0.5 mm )
increased the cell cycle inhibitor
p27 kip expression significantly, whereas the AMPK inhibitor ( compound C, 20 microm ) and FSH reduced p27kip expression significantly compared with control
Short et al., Mol Carcinog 2010
:
AMPK mediated phosphorylation of murine
p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stability ... In addition, activation of
AMPK led to phosphorylation of
p27 at the conserved terminal threonine residue of murine p27 ( T197 ) in both in vitro kinase assays and in cells ... Furthermore, activation of
AMPK signaling
promoted the interaction between
p27 and 14-3-3 proteins and increased the stability of the p27 protein in a manner that was dependent on T197