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ABCB1 — FOS
Text-mined interactions from Literome
Ogretmen et al., Biochemistry 1999
(Breast Neoplasms) :
Negative
regulation of
MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross coupled NF-kappa B/p65 and
c-Fos transcription factors and their interaction with the CAAT region
Roy et al., Cancer Chemother Pharmacol 2010
(Carcinoma, Hepatocellular...) :
Further studies revealed the
involvement of
AP-1 in the celecoxib induced downregulation of
MDR1 expression
Nishanth et al., Eur J Pharmacol 2010
(Carcinoma, Hepatocellular...) :
Further studies reveal the involvement of NF-?B and
AP-1 in the C-PC
induced down regulation of
MDR1
Fang et al., Anat Rec (Hoboken) 2012
(Carcinoma, Hepatocellular...) :
Our results demonstrated that mda-7/IL-24 could restore the drug sensitivity through the downregulation of
MDR1 , MRP1, and LRP expression, as well as the transcriptional
activation of
AP-1 and NF-?B and effectively reverse MDR
Choi et al., Evidence-based complementary and alternative medicine : eCAM 2013
:
Consistently, overexpression of JNK1, c-Jun, or
c-Fos inhibited YB-1 dependent
MDR1 expression and reduced viabilities in MCF-7/Dox cells