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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ABCB1 — FOS

Text-mined interactions from Literome

Ogretmen et al., Biochemistry 1999 (Breast Neoplasms) : Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region
Roy et al., Cancer Chemother Pharmacol 2010 (Carcinoma, Hepatocellular...) : Further studies revealed the involvement of AP-1 in the celecoxib induced downregulation of MDR1 expression
Nishanth et al., Eur J Pharmacol 2010 (Carcinoma, Hepatocellular...) : Further studies reveal the involvement of NF-?B and AP-1 in the C-PC induced down regulation of MDR1
Fang et al., Anat Rec (Hoboken) 2012 (Carcinoma, Hepatocellular...) : Our results demonstrated that mda-7/IL-24 could restore the drug sensitivity through the downregulation of MDR1 , MRP1, and LRP expression, as well as the transcriptional activation of AP-1 and NF-?B and effectively reverse MDR
Choi et al., Evidence-based complementary and alternative medicine : eCAM 2013 : Consistently, overexpression of JNK1, c-Jun, or c-Fos inhibited YB-1 dependent MDR1 expression and reduced viabilities in MCF-7/Dox cells