El Mkadem et al., Diabetes 2001
(Insulin Resistance...) :
Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome
Thameem et al., Diabetes 2012
(Diabetes Mellitus, Type 2) :
Expression of IRS1 mutant Arg972 in human mesangial cells significantly reduced the insulin stimulated phosphorylation of IRS1 and Akt kinase
Huang et al., J Hypertens 2012
(Hypertension) :
This study for the first time provides insights into the role of Arg ( 972 ) IRS-1 in hypertension