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ARHGEF7 — GRAP2

Text-mined interactions from Literome

Lee et al., J Biol Chem 2001 : This betaPix induced p38 activation was blocked by coexpression of dominant negative Cdc42/Rac or kinase-inactive PAK, indicating that the effect of betaPix on p38 is exerted through the Cdc42/Rac-PAK pathway and requires PAK kinase activity
Ahn et al., Cancer Lett 2003 (Breast Neoplasms) : The overexpression of betaPix enhances the activation of p38 , which is thought to be an important downstream effector of the Rho GTPase family ( Rac, Cdc42 ), which are involved in increased membrane ruffling and cell motility
Seo et al., J Biol Chem 2004 : UV-induced p38 activation by Gbetagamma was blocked by overexpression of dominant negative p21 activated kinase (PAK) interacting exchange factor beta ( betaPix ), and wild type betaPix stimulated the UV-induced p38 activation, which was blocked by N17 Cdc42