Capano et al., Biochem J 2006
(Myocardial Ischemia) :
The AMPK activators AICAR ( 5-aminoimidazole-4-carboxamide ribonucleoside ) and metformin also stimulated Bax translocation
Zhang et al., J Biol Chem 2010
(Glioblastoma) :
In further studies, we found that activation of AMPK is involved in TMZ induced p53 activation and subsequent p21, Noxa, and Bax up-regulation
Kim et al., Biochem Biophys Res Commun 2013
:
We also confirmed that triggering activation of AMPK by various factors resulted in an increase of Bax gene expression