Gene interactions and pathways from curated databases and text-mining

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CAPN12 — RHOA

Text-mined interactions from Literome

Kulkarni et al., J Biol Chem 2002 : Here we show that mu-calpain is also involved in inactivating RhoA during integrin induced signaling
Yoo et al., J Biol Chem 2010 (Cell Transformation, Neoplastic...) : We also found that ras activates a GTPase RhoA , that RhoA promotes activation of a protease calpain , and that calpain triggers degradation of Beclin-1, a critical mediator of autophagy, in these cells