Gene interactions and pathways from curated databases and text-mining

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CASP12 — PLD1

Text-mined interactions from Literome

Lee et al., Eur J Immunol 2004 : The reduction in PLD1a protein level was blocked by caspase inhibitors
Raymond et al., Endocrinology 2006 (Leiomyoma...) : A pharmacological approach showed that the effect of ET-1 on caspase-3/7 activation in ELT3 cells was not dependent on phosphatidylinositol 3-kinase, ERK1/2, or phospholipase D activities
Jang et al., J Biol Chem 2011 : Recently, we reported that caspase mediated cleavage of PLD1 generates the N-terminal fragment ( NF-PLD1 ) and C-terminal fragment ( CF-PLD1 )
Kasai et al., J Immunol 1998 : The caspase inhibitors, z-DEVD and z-VAD, effectively suppressed PLD activation and apoptosis, but UFA release was unaffected