Gene interactions and pathways from curated databases and text-mining

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CDH1 — PAK1

Text-mined interactions from Literome

Elloul et al., Clin Exp Metastasis 2010 (Ovarian Neoplasms...) : E-cadherin expression and regulation by Snail and Pak1 were studied in ES-2 and OVCAR-3 ovarian cancer cells in vitro
Pirraglia et al., Development 2010 : Pak1 mediates these effects by decreasing and increasing E-cadherin levels at the adherens junctions and basolateral membrane, respectively, through Rab5- and Dynamin dependent endocytosis
Yan et al., Stroke 2013 (Subarachnoid Hemorrhage) : Downstream to PAR-1, c-Src dependent activation of p21 activated kinase-1 led to an increased serine/threonine phosphorylation of vascular endothelial-cadherin ; immunoprecipitation results revealed an enhanced binding of phosphorylated vascular endothelial-cadherin with endocytosis orchestrator ß-arrestin-2