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CDH5 — RHOA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Nelson et al., Mol Biol Cell 2004
:
Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating
RhoA
Ordóñez-Morán et al., J Cell Biol 2008
(Colonic Neoplasms) :
As shown by the use of chemical inhibitors, dominant negative mutants and small interfering RNA,
RhoA-ROCK , and p38MAPK-MSK1 activation is
necessary for the induction of
CDH1/E-cadherin , CYP24, and other genes and of an adhesive phenotype by 1,25 ( OH ) ( 2 ) D ( 3 )
Espejo et al., Am J Physiol Cell Physiol 2010
(Colonic Neoplasms) :
Adherens junction assembly is impaired following calcium switch in KM12C cells with stably knocked down PTP-PEST and is accompanied by an increase in the activity of Rac1 and a suppression of
RhoA activity in
response to
cadherin engagement