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CNR1 — EPHB2

Text-mined interactions from Literome

Galve-Roperh et al., Mol Pharmacol 2002 (Astrocytoma) : However, the precise molecular mechanism for CB(1) mediated ERK activation is still unknown ... In conclusion, CB(1) induced ERK activation was mediated by PI3K ( IB ) and this effect may have important consequences in the control of cell death/survival decision
Davis et al., J Biol Chem 2003 (Neuroblastoma) : A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells ... These data implicate the inhibition of PKA as the predominant pathway for ERK activation by CB1 receptors in N1E-115 cells
Zhao et al., J Biol Chem 2005 (Cell Transformation, Neoplastic) : Using CB1/2-/- murine embryonic fibroblasts, we present the first direct evidence that both cannabinoid receptors 1 and 2 (CB1/2) are involved in 2-AG induced ERK activation
Graham et al., J Biol Chem 2006 (MAP Kinase Signaling System) : CB1 stimulation with HU210 activated ERK and induced the transcription factor Krox-24
Daigle et al., Neuropharmacology 2008 : CB(1) receptor stimulation by the potent CB(1) receptor agonist, CP 55,940 transiently activated ERK1/2
Wu et al., Bone 2011 : Cannabinoid receptor 1 regulates ERK and GSK-3ß dependent glucocorticoid inhibition of osteoblast differentiation in murine MC3T3-E1 cells ... CB1 signaling regulated JNK, ERK , GSK-3ß, and Akt activation as well as Runx2 and IGF-I expression
Franklin et al., Pharmacol Res 2013 : Additionally, inhibition of clathrin mediated endocytosis, ERK1/2 , and the AP-1 transcription factor also prevented the cannabinoid receptor induced upregulation of ß-Arrestin 2