Gene interactions and pathways from curated databases and text-mining

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CNTNAP1 — RAC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Harnois et al., Oncogene 2003 : Nevertheless, Rac1 and Cdc42, but not RhoA, are activated by p190 ( bcr-abl ) in vitro and in vivo
Wildenberg et al., Cell 2006 : Receptor induced Rac activity causes translocation of p190RhoGAP to adherens junctions ( AJs ), where it couples to the cadherin complex via interaction with p120
Daubon et al., Oncogene 2008 : We previously reported that p210 ( bcr-abl ) activates RhoA and Rac1, while p190 ( bcr-abl ) although devoid of a Dbl-homology ( DH ) domain activates Rac1 , but not RhoA
Bustos et al., Curr Biol 2008 : Moreover, activated Rac1 is sufficient to recruit p190B into a detergent-insoluble membrane fraction, a process that is accompanied by a decrease in GTP bound RhoA from membranes
Birukova et al., Exp Cell Res 2011 (Disease Models, Animal...) : OxPAPC also induced Rac dependent tyrosine phosphorylation and association of p190RhoGAP with AJ protein p120-catenin