Gene interactions and pathways from curated databases and text-mining

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CREB5 — PDGFB

Text-mined interactions from Literome

Stevenson et al., Exp Cell Res 2001 (Calcium Signaling) : Block of Ran mediated nuclear import, by wheat germ agglutinin or an inactivating Ran mutant ( T24N Ran ), significantly reduced nuclear P-CREB in response to PDGF-BB or membrane depolarization, but enhanced levels of P-CREB in response to forskolin ... Furthermore, blocking nuclear export with leptomycin B reduced P-CREB stimulation by both depolarization and PDGF-BB
Jiang et al., Chem Biol Interact 2008 : Preincubation of RASMCs with 9 microM PNN resulted in a significant inhibition of PDGF-BB induced extracellular signal regulated kinase1/2 ( ERK1/2 ) phosphorylation expression and PDGF-BB induced CREB phosphorylation expression
Yao et al., J Neurosci 2012 : Blocking TRPC1 channel suppressed PDGF mediated proliferation as well as PDGF-BB induced ERK/CREB and mTOR/4E-BP-p70S6K activation, thereby underscoring its role in this process