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CRH — JUN

Text-mined interactions from Literome

Zbytek et al., J Cell Physiol 2005 : CRH also increased activator protein-1 DNA binding activity with JunD identified as the most important element
Uh et al., Reproductive biology and endocrinology : RB&E 2009 : Classically protein kinase A (PKA) and transcription factor activator protein 1 (AP-1) mediate the cyclic AMP ( cAMP ) induced-corticotrophin releasing hormone (CRH) expression in the placenta
Autelitano et al., J Neuroendocrinol 1994 (Pituitary Neoplasms) : Although DEX treatment of AtT-20 cells did not affect AP-1 DNA binding capacity of nuclear extracts, DEX pretreatment blunted the stimulation of AP-1 binding in response to CRF ... High levels of DEX treated extracts led to a relative repression of CRF induced AP-1 binding, suggesting that ligand activated GR may lower available AP-1 levels by direct protein : protein interaction ... These data suggest that in the corticotrope cell relatively high levels of activated GR may influence CRF induced AP-1 DNA binding via transient genomic actions on basal c-jun and stimulated c-fos and/or via direct protein : protein interactions
Itoi et al., Endocrinology 1996 (Hypoglycemia) : Antisense oligodeoxyribonucleotides ( oligos ) directed against c-fos, c-jun, or the cAMP response element binding protein ( CREB ) mRNA were injected into both PVN before insulin induced hypoglycemia to assess whether activator protein-1 or CREB mediates transcriptional activation of CRF during hypoglycemia