Gene interactions and pathways from curated databases and text-mining

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CSF2 — NOS2

Text-mined interactions from Literome

Wanner et al., Langenbecks Arch Surg 1999 (Endotoxemia) : rG-CSF per se did not affect NOS II , CINC, or ICAM-1 expression in hepatic liver cells, while LPS induced a marked expression of NOS II, CINC, and ICAM-1 in nonparenchymal cells and, to a lesser extent, in hepatocytes
Cruz et al., Immunol Cell Biol 2001 : Granulocyte-macrophage colony stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line ... Together, these results show that GM-CSF induces iNOS expression in skin dendritic cells by a mechanism involving activation of the NF-kappaB pathway
Vital et al., Mediators Inflamm 2003 : Dexamethasone prevents granulocyte-macrophage colony stimulating factor induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line ... GM-CSF induced iNOS expression and NO production, and activated the transcription factor NF-kappaB ... The corticosteroid dexamethasone inhibits GM-CSF induced NF-kappaB activation, iNOS protein expression and NO production
Chen et al., Toxicology 2004 : The results demonstrated that NO production, mRNA levels of iNOS , IL-1beta, TNF-alpha were down regulated by MC-LR dose-dependently and mRNA levels of GM-CSF and IFN-gamma were also decreased but in dose independent manner
Carryn et al., J Infect Dis 2004 (Listeriosis) : GM-CSF stimulates the release of TNF-alpha and the expression of iNOS
Oppeltz et al., Cytokine 2012 (Burns) : Inhibition of iNOS activity in WT mice with L-Nil suppressed burn wound levels of IL-1ß, G-CSF , and MIP-1a, whereas IL-6, TNF-a, KC, MCP-1 and MIP-1ß were unaffected
Hauber et al., Cell Immunol 1997 : We show that gene expression of IL-1 alpha, IL-1 beta, IL-6, granulocyte-colony stimulating factor , and IL-10 was induced in both cell fractions, whereas increased mRNA levels of interferon-gamma and the inducible nitric oxide synthase were exclusively detected in the patients ' nonadherent MNCs