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CDKN1A — CXCL10

Text-mined interactions from Literome

Zhang et al., Mol Cell Biol 2005 : In the characterization of the IP10 induced apoptotic pathway, we found that overexpression of IP10 upregulated p53 and resulted in altered expression of p53-responsive genes such as the p21Cip1 , p27kip1, NF-kappaB, Bax, and PUMA genes and the mitochondrial translocation of Bax
Schulthess et al., Cell Metab 2009 (Diabetes Mellitus) : CXCL10 induced sustained activation of Akt, JNK, and cleavage of p21 activated protein kinase 2 (PAK-2) , switching Akt signals from proliferation to apoptosis