Gene interactions and pathways from curated databases and text-mining

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CXCR3 — EPHB2

Text-mined interactions from Literome

Xia et al., J Neuroimmunol 2000 (Alzheimer Disease...) : Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes : in vitro ERK1/2 activation and role in Alzheimer 's disease
Bonacchi et al., J Biol Chem 2001 : In MC, which respond to CXCR3 ligands with increased DNA synthesis, CXCR3 activation resulted in a biphasic stimulation of ERK activation, a pattern similar to the one observed in HSC exposed to platelet derived growth factor, indicating that this type of response is related to the stimulation of cell proliferation
Goldberg-Bittman et al., Cytokine 2005 (Neuroblastoma) : The role of a CXCR3-like receptor in Erk phosphorylation was substantiated by the ability of CXCL11, another potent CXCR3 ligand, to induce Erk phosphorylation in the NUB6 and SK-NMC cells
Aksoy et al., Am J Physiol Lung Cell Mol Physiol 2006 : Stimulation of CXCR3 with I-TAC enhanced thymidine incorporation and cell proliferation and increased p38 and ERK1/2 phosphorylation
Dar et al., Immunology 2007 : The ZAP-70 inhibitor piceatannol reduced CXCR3 mediated tyrosine phosphorylation of ZAP-70, LAT, PLCgamma1 and mitogen activated protein kinase Erk and it reduced CXCL10 mediated chemotaxis of both CXCR3 transfected Jurkat T cells and normal T cells expressing CXCR3