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CXCR3 — EPHB2
Text-mined interactions from Literome
Xia et al., J Neuroimmunol 2000
(Alzheimer Disease...) :
Expression of the chemokine receptor
CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes : in vitro
ERK1/2 activation and role in Alzheimer 's disease
Bonacchi et al., J Biol Chem 2001
:
In MC, which respond to CXCR3 ligands with increased DNA synthesis,
CXCR3 activation
resulted in a biphasic stimulation of
ERK activation, a pattern similar to the one observed in HSC exposed to platelet derived growth factor, indicating that this type of response is related to the stimulation of cell proliferation
Goldberg-Bittman et al., Cytokine 2005
(Neuroblastoma) :
The
role of a
CXCR3-like receptor in
Erk phosphorylation was substantiated by the ability of CXCL11, another potent CXCR3 ligand, to induce Erk phosphorylation in the NUB6 and SK-NMC cells
Aksoy et al., Am J Physiol Lung Cell Mol Physiol 2006
:
Stimulation of
CXCR3 with I-TAC enhanced thymidine incorporation and cell proliferation and
increased p38 and
ERK1/2 phosphorylation
Dar et al., Immunology 2007
:
The ZAP-70 inhibitor piceatannol reduced
CXCR3 mediated tyrosine phosphorylation of ZAP-70, LAT, PLCgamma1 and mitogen activated protein kinase
Erk and it reduced CXCL10 mediated chemotaxis of both CXCR3 transfected Jurkat T cells and normal T cells expressing CXCR3