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ATP5O — DDT

Text-mined interactions from Literome

Bircsak et al., J Biochem Mol Toxicol 2013 : Using plasma membranes from cells overexpressing MDR1 and BCRP, it was demonstrated that the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) ( o, p'-DDT and p, p'-DDT isomers ) as well as its metabolite ( p, p'-dichlorodiphenyldichloroethane ), inhibit both MDR1 and BCRP ATPase activity
Hennighausen et al., Arch Toxicol Suppl 1985 : In rat but not in mouse thymocytes the ecto-ATPase was inhibited in vitro by HgCl2, tricyclohexyltin chloride, di-n-butyltin dichloride, DDT , gamma HCH and desipramine
Wärngård et al., Chem Biol Interact 1988 : As the effects of calcium are closely associated with the multifunctional protein calmodulin (CaM) in most cells the potential binding of DDT to CaM and subsequent effects on CaM stimulated Ca2+/Mg2+-ATPase activity were studied ... DDT inhibited CaM stimulated Ca2+/Mg2+-ATPase activity and bound to CaM in a manner similar to established CaM-inhibitors
Mourelle et al., J Appl Toxicol 1985 : DDT , but not toxaphene, also led to a decrease in Mg2+-ATPase ( 20 % ) and Ca2+-ATPase ( 35 % ) activity
Nishihara et al., Food Chem Toxicol 1985 : These results indicate that DDT inhibits ATPase itself
Ghiasuddin et al., Biochem Pharmacol 1982 : The effects of DDT and permethrin on inhibition of reconstituted Ca-ATPase were higher when the insecticide was first added to the protein portion and the enzyme was then reconstituted with the phospholipids, than when the same amount of insecticide was first added to the phospholipids which were then used for reconstitution
Ohyama et al., Biochem Pharmacol 1982 : The effects of dichlorodiphenyltrichloroethane (DDT) and sixteen analogues on respiration, swelling and latent ATPase of rat liver mitochondria were examined systematically