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CASP4 — EGFR

Text-mined interactions from Literome

Bae et al., FEBS Lett 2001 : We have found that treatment of A431 cells with tumor necrosis factor-alpha in the presence of cycloheximide resulted in the cleavage of epidermal growth factor receptor (EGFR) as well as the activation of caspase-3 ... We also investigated the effect of caspase dependent cleavage of EGFR upon the mediation of signals to downstream signaling molecules such as PLC-gamma1
Keese et al., Differentiation 2007 (Colorectal Neoplasms) : We have studied caspase-3 activation by combined DNA damage induction and EGFR kinase inhibition in order to identify potential EGFR mediated survival signals conferring resistance to apoptosis in human colorectal tumor cells
Ge et al., Biol Reprod 2009 : On the other hand, inhibition of EGFR , Ca ( 2+ ) /PKC, or NFKB1 abolished the EGF stimulated increase in the expression of cyclins CCND1 and CCNE1, cyclin dependent kinase 6 (CDK6), CDK2, and BCL2, and restored the EGF induced inhibition of BAX expression and caspase 3/9 activity, indicating that EGFR, PKC, and NFKB1 signaling cascades were involved in EGF stimulated DNA synthesis and antiapoptosis action
Lokeshwar et al., Cancer Res 2010 (Neoplasm Invasiveness...) : 4-MU induced caspase-8, caspase-9, and caspase-3 activation, PARP cleavage, upregulation of Fas-L, Fas, FADD and DR4, and downregulation of bcl-2, phosphorylated bad, bcl-XL, phosphorylated Akt, phosphorylated IKB, phosphorylated ErbB2, and phosphorylated epidermal growth factor receptor
Adam et al., Hum Reprod 2012 : DCN, like epidermal GF, phosphorylated EGFR significantly ( P < 0.05 ) and reduced the activity of caspase 3/7 in cultured GCs