Gene interactions and pathways from curated databases and text-mining

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EPHB2 — TRAF6

Text-mined interactions from Literome

Yeo et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Overexpression of DN-TRAF6 suppressed CpG DNA mediated activation of p38 and JNK, but not ERK , explaining the partial inhibitory effects of DN-TRAF6 on CpG DNA induced COX2-3'-UTR-luciferase activity
Loniewski et al., Mol Immunol 2007 : We demonstrate here that reduced level of TRAF6 ( approximately 80 % decrease ) in macrophages does not significantly affect any of the components of the TLR4 stimulated ERK pathway, including p105 phosphorylation, TPL2 degradation and ERK1/2 phosphorylation
Kashiwada et al., J Exp Med 1998 : Here we report that transient expression of TRAF6 stimulated both ERK and NF kappa B activity in the 293 cell line ... Coexpression of the dominant negative H-Ras did not affect TRAF6 mediated ERK activity, suggesting that TRAF6 may activate ERK along a Ras independent pathway