Gene interactions and pathways from curated databases and text-mining

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EGF — EREG

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Inatomi et al., Int J Mol Med 2006 : Among the various cytokines and growth factors, interleukin-1beta, tumor necrosis factor-alpha, and EGF strongly induced amphiregulin and epiregulin mRNA expression
Morita et al., Molecular vision 2007 : Epiregulin increased the expression of HB-EGF and AR, while TGF-alpha, HB-EGF , AR, and EGF increased the expression of epiregulin in HCECs
Taylor et al., Proc Natl Acad Sci U S A 1999 : In addition, epiregulin caused rapid EGF receptor activation in RASM cells