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F2R — VEGFA
Text-mined interactions from Literome
Yin et al., FASEB J 2003
(Cell Transformation, Neoplastic...) :
Specific inhibitors of protein kinase C ( PKC ), Src, and phosphatidylinositol 3-kinase (PI3K) inhibit
Par1 induced
VEGF expression, suggesting the participation of these kinases in the process
Ma et al., Proc Natl Acad Sci U S A 2005
:
In the present study, we have attempted to determine the
roles of
PAR1 and PAR4 in regulating release of endostatin and
VEGF from human platelets
Bian et al., Invest Ophthalmol Vis Sci 2007
:
hRPE
VEGF expression is predominantly protease activated receptor
(PAR)-1 dependent
Melnikova et al., Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2008
:
Notably, in many tumor types including melanoma,
PAR-1 expression directly correlates with their metastatic phenotype and is directly
responsible for the expression of interleukin-8, matrix metalloproteinase-2 (MMP-2),
vascular endothelial growth factor , platelet derived growth factor, and integrins
Osuga et al., Front Biosci (Elite Ed) 2012
(Endometriosis) :
PAR1 activation in endometrial stromal cells
induces production of
vascular endothelial growth factor and matrix metalloproteinases, and increases activities of tissue-type and urokinase-type plasminogen activator
Osuga et al., Front Biosci (Schol Ed) 2012
(Endometriosis) :
PAR1 activation in endometrial stromal cells
induces production of
vascular endothelial growth factor and matrix metalloproteinases, and increases activities of tissue-type and urokinase-type plasminogen activator