Gene interactions and pathways from curated databases and text-mining

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FGF2 — RAC2

Text-mined interactions from Literome

Jackson et al., Mol Endocrinol 2003 (MAP Kinase Signaling System...) : Moreover, expression of dominant negative Rac also attenuated FGF-2 and FGF-4 stimulation of MAPK ( ERK )
Maddala et al., Molecular vision 2003 : Rac GTPase activation, in contrast, was significantly enhanced in response to only EGF or b-FGF
Yan et al., Mol Cell Biol 2008 : Finally, the activation levels of extracellular signal regulated kinase ( ERK ), p38, and Rac , which are important signaling molecules in angiogenesis, were all reduced in response to FGF2 when either of the Rap1 proteins was depleted