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GCG — PRKAG2

Text-mined interactions from Literome

Berglund et al., Am J Physiol Endocrinol Metab 2010 : The hypothesis that increases in hepatic glucagon action stimulate AMP activated protein kinase (AMPK) signaling and peroxisome proliferator activated receptor-a ( PPARa ) and fibroblast growth factor 21 (FGF21) expression in a manner modulated by fatty acids was tested in vivo ... Clamp results in gcgr ( +/+ ) mice demonstrate that hyperlipidemia does not independently impact or modify glucagon stimulated increases in hepatic AMP/ATP, p-AMPK ( Thr ( 172 ) ), or PPARa and FGF21 mRNA
Rivera et al., J Clin Invest 2010 (Diabetes Mellitus, Type 1...) : Furthermore, hypoglycemia and glucagon had an additive effect on the activation of AMPK , which was associated with altered activity of the enzymes of glycogen metabolism