Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Heo et al., Toxicol In Vitro 2004 (Breast Neoplasms) : To test the effect of SNL glycoprotein on the DNA binding activities of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) , and nitric oxide ( NO ) production, these experiments were carried out using electrophoretic mobility shift assays ( EMSA ), western blot analysis, and the Griess method ... Results in this experiment showed that SNL glycoprotein inhibits 12-O-Tetra decanoylphorbol-13-acetate ( TPA ; 100 nM ) -induced DNA binding activities of NF-kappaB and AP-1 , and enhances NO production in MCF-7 cells
Comerford et al., Cancer Res 2004 : c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha dependent P-glycoprotein expression in hypoxia
Ko et al., Toxicol In Vitro 2005 : We also demonstrated that RVS glycoprotein inhibits activities of the nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) induced by G/GO, and prevents from G/GO induced apoptosis in the NIH/3T3 cells
Zhou et al., Cancer Res 2006 (Pancreatic Neoplasms...) : In this study, we show that adenovirus mediated enhancement of the c-Jun NH2-terminal kinase (JNK) reduces the level of P-glycoprotein in a dose- and time dependent manner
Lee et al., Mol Cell Biochem 2007 : UDN glycoprotein inhibits activator protein-1 and matrix metalloproteinase-9 via blocking of oxygen radicals in HT-29 cells ... In addition, UDN glycoprotein blocked the DNA binding activity of activator protein-1 (AP-1) through suppression of c-Jun and c-Fos activities, respectively
Lee et al., Cancer Lett 2007 (Colonic Neoplasms) : UDN glycoprotein regulates activities of manganese-superoxide dismutase, activator protein-1 , and nuclear factor-kappaB stimulated by reactive oxygen radicals in lipopolysaccharide stimulated HCT-116 cells ... The results obtained from electrophoretic mobility shift assay ( EMSA ) and Western blot analysis showed that UDN glycoprotein blocks the DNA binding activities of nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) , and attenuates the activities of NF-kappaB subunits ( p50 and p65 ), and AP-1 subunits ( c-Jun and c-Fos ), respectively
Lee et al., Toxicol Appl Pharmacol 2007 (Colonic Neoplasms...) : Also, 0.02 % UDN glycoprotein suppressed the DNA binding activities of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) , accompanying the inhibitions of its subunits ( p50, p65, c-Jun, and c-Fos ), pro-inflammatory proteins [ inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) ], and pro-inflammatory cytokines [ tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 ] on DMH stimulated ACF formation
Lee et al., J Nutr Biochem 2009 : In the G/GO or HX/XO stimulated transcriptional activity, ZPDC glycoprotein also blocked the DNA binding activities of nuclear factor-kappa B and activator protein-1 and attenuated the activities of p50, p65, c-Jun and c-Fos, respectively
Oh et al., Inflammation 2011 (Hypersensitivity...) : We also found that the CTB glycoprotein reduced arachidonic acid release, COX-2 expression, and AP-1 transcriptional activation through p38 MAPK phosphorylation in DEHP treated RBL-2H3 cells