Gene interactions and pathways from curated databases and text-mining

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GSPT2 — TP53

Text-mined interactions from Literome

Yang et al., Mol Cell Biochem 2007 : In contrast, over expression of H179Y-mutant p53 promoted G1 to S phase transition with enlarged cell size and increased cyclin A1 and Cdk4 expression in HELF cells
Zhang et al., Oncogene 1997 : Inhibition of the growth of WI-38 fibroblasts by benzyloxycarbonyl-Leu-Leu-Tyr diazomethyl ketone : evidence that cleavage of p53 by a calpain-like protease is necessary for G1 to S-phase transition