Gene interactions and pathways from curated databases and text-mining

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IFI27 — MYLIP

Text-mined interactions from Literome

le Sage et al., EMBO J 2007 (Neoplasms) : Regulation of the p27 ( Kip1 ) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
Igoucheva et al., Biochem Biophys Res Commun 2009 (Melanoma...) : Moreover, a series of functional assays demonstrated that mir-221 could directly inhibit cKit, p27 ( Kip1 ) and, possibly, other pivotal proteins in melanoma
Corbetta et al., Endocr Relat Cancer 2010 (Adenoma...) : Finally, miR-296 and miR-222 levels negatively correlated with mRNA levels of the hepatocyte growth factor receptor regulated tyrosine kinase substrate and p27/kip1 levels respectively
Lu et al., Blood 2011 : Silencing of miR-221 or overexpressing of miR-155 in DCs resulted in p27 ( kip1 ) protein increase and DC apoptosis ... Furthermore, we provide evidence that miR-155 indirectly regulated p27 ( kip1 ) protein level by targeting Kip1 ubiquitination promoting complex 1
Sun et al., Mol Cancer Ther 2012 (Stomach Neoplasms) : Luciferase assays revealed that miR-196a inhibited p27 ( kip1 ) expression by targeting one binding site in the 3'-untranslated region ( 3'-UTR ) of p27 ( kip1 ) mRNA
Wang et al., FEBS Lett 2013 (Retinoblastoma) : Furthermore, overexpression of miR-365b-3p upregulates p21 and p27 but downregulates cdc2 and Cyclin D1 protein levels