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IL1A — PML
Text-mined interactions from Literome
Lo et al., Blood 2013
:
In addition, downregulation of
PML by arsenic trioxide
suppressed monosodium urate ( MSU ) -induced
IL-1ß production, suggesting that targeting to PML could be used to treat NLRP3 inflammasome associated diseases
Heuser et al., Mediators Inflamm 1998
(Leukemia, Promyelocytic, Acute) :
We investigated the
regulation of human
PML expression by interferons ( IFNs ) and
IL-1 in various human haematopoietic lines ( U937, THP1, HL60, NB4 ), in human diploid fibroblasts and in human peripheral blood leukocytes ... Our data suggest that
stimulation of
PML expression by interferons and
IL-1 may account for upregulation of PML proteins observed in inflammatory tissues and in proliferative states