Gene interactions and pathways from curated databases and text-mining

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IL1A — PML

Text-mined interactions from Literome

Lo et al., Blood 2013 : In addition, downregulation of PML by arsenic trioxide suppressed monosodium urate ( MSU ) -induced IL-1ß production, suggesting that targeting to PML could be used to treat NLRP3 inflammasome associated diseases
Heuser et al., Mediators Inflamm 1998 (Leukemia, Promyelocytic, Acute) : We investigated the regulation of human PML expression by interferons ( IFNs ) and IL-1 in various human haematopoietic lines ( U937, THP1, HL60, NB4 ), in human diploid fibroblasts and in human peripheral blood leukocytes ... Our data suggest that stimulation of PML expression by interferons and IL-1 may account for upregulation of PML proteins observed in inflammatory tissues and in proliferative states