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IL2 — PPP2CA

Text-mined interactions from Literome

Ross et al., J Biol Chem 2010 : Moreover, inhibition of PP2A , but not PP1, diminished IL-2 induced tyrosine phosphorylation of IL-2Rbeta , JAK3, and STAT5, and abolished STAT5 DNA binding activity
Brockdorff et al., Tissue Antigens 1997 : In conclusion, we provide evidence, for the first time, that IL-2 induces a transient downregulation of PP2A activity in T cells
Brockdorff et al., Cytokine 1997 : We show that calyculin A, a potent inhibitor of PP1 and PP2A, blocks PP1/PP2A activity and IL-2 induced adhesion, whereas cyclosporin A, an inhibitor of protein serine/threonine phosphatase 2B (PP2B), does not, suggesting that PP1 and/or PP2A are involved in IL-2 induced adhesion