Gene interactions and pathways from curated databases and text-mining

◀ Back to PLD1

IL6 — PLD1

Text-mined interactions from Literome

Conquer et al., Osteoarthritis Cartilage 1994 : Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes
Radeff et al., Cell Signal 2004 (Bone Resorption) : Role of protein kinase A, phospholipase C and phospholipase D in parathyroid hormone receptor regulation of protein kinase Calpha and interleukin-6 in UMR-106 osteoblastic cells ... This is the first demonstration that PLD mediated signalling leads to both PKC-alpha translocation and IL-6 promoter activation in osteoblastic cells
Sethu et al., J Immunol 2008 (Calcium Signaling...) : Furthermore, use of antisense oligonucleotides to reduce expression of PLD1 or PLD2 demonstrated that PLD1 is required for TNF-alpha induced production of several important cytokines, such as IL-1beta, IL-5, IL-6 , and IL-13, in human monocytes
L'Heureux et al., Blood 1995 : Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils : interleukin-8 , but not NAP-2 or GRO alpha, stimulates phospholipase D activity