UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to IRS1

INPP5D — IRS1

Pathways - manually collected, often from reviews:

NCI Pathway Database Insulin Pathway: Insulin Receptor/Insuli/IRS1/GRB2/SHC complex (INSR-INS-SHC1-GRB2-IRS1) → SHIP (INPP5D) (modification, collaborate) Wada et al., Endocrinology 1999, Sharma et al., Mol Endocrinol 2005, Kovacina et al., Biochem Biophys Res Commun 1993, Skolnik et al., Science 1993, Pronk et al., J Biol Chem 1993, Skolnik et al., EMBO J 1993, Ishihara et al., J Biol Chem 1997
Evidence: assay
NCI Pathway Database Insulin Pathway: Insulin Receptor/Insuli/IRS1/GRB2/SHC complex (INSR-INS-SHC1-GRB2-IRS1) → SHC/SHIP complex (SHC1-INPP5D) (modification, collaborate)
Wada et al., Endocrinology 1999, Sharma et al., Mol Endocrinol 2005, Kovacina et al., Biochem Biophys Res Commun 1993, Skolnik et al., Science 1993, Pronk et al., J Biol Chem 1993, Skolnik et al., EMBO J 1993, Ishihara et al., J Biol Chem 1997
Evidence: assay
NCI Pathway Database Insulin Pathway: Insulin Receptor/Insulin/IRS1 complex (INSR-INS-IRS1) → SHIP (INPP5D) (modification, collaborate) Wada et al., Endocrinology 1999, Sharma et al., Mol Endocrinol 2005, Kovacina et al., Biochem Biophys Res Commun 1993, Skolnik et al., Science 1993, Pronk et al., J Biol Chem 1993, Skolnik et al., EMBO J 1993, Ishihara et al., J Biol Chem 1997
Evidence: assay
NCI Pathway Database Insulin Pathway: Insulin Receptor/Insulin/IRS1 complex (INSR-INS-IRS1) → SHC/SHIP complex (SHC1-INPP5D) (modification, collaborate)
Wada et al., Endocrinology 1999, Sharma et al., Mol Endocrinol 2005, Kovacina et al., Biochem Biophys Res Commun 1993, Skolnik et al., Science 1993, Pronk et al., J Biol Chem 1993, Skolnik et al., EMBO J 1993, Ishihara et al., J Biol Chem 1997
Evidence: assay
NCI Pathway Database Insulin Pathway: Insulin Receptor/Insulin/IRS1 complex (INSR-INS-IRS1) → SHIP (INPP5D) (modification, activates) Wada et al., Endocrinology 1999
NCI Pathway Database Insulin Pathway: Insulin Receptor/Insuli/IRS1/GRB2/SHC/Sos complex (INSR-INS-SHC1-SOS1-GRB2-IRS1) → SHC/SHIP complex (SHC1-INPP5D) (modification, activates)
Wada et al., Endocrinology 1999, Sharma et al., Mol Endocrinol 2005, Pronk et al., Mol Cell Biol 1994, Sasaoka et al., J Biol Chem 1994, Myers et al., Mol Cell Biol 1994
Evidence: assay