Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
INSR
→
Complex of IRS2-YWHAE
(decreases, IRS2/YWHAE Activity)
Evidence: both the insulin receptor and IRS proteins undergo serine phosphorylation, which may attenuate signalling by decreasing insulin-stimulated tyrosine phosphorylation19 and promote interaction with 14-3-3 proteins20.