Gene interactions and pathways from curated databases and text-mining

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IL6 — IRG1

Text-mined interactions from Literome

Kang et al., Stem Cells Dev 2008 : Moreover, TNF-alpha production significantly decreased, whereas TGF-beta, IL-6 , and interferon-gamma production significantly increased in cAD-MSCs that were cocultured with leukocytes
Li et al., J Biol Chem 2013 (Sepsis) : IRG1 significantly suppressed TLR triggered production of proinflammatory cytokines TNF-a, IL-6 , and IFN-ß in LPS tolerized macrophages, with the elevated expression of reactive oxygen species ( ROS ) and A20