◀ Back to STAT3

MAP2K4 — STAT3

Text-mined interactions from Literome

Schuringa et al., Biochem J 2000 (Carcinoma, Hepatocellular...) : Interleukin-6 induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components ... However, SEK-1/MKK-4 [ where SEK-1 stands for stress activated protein kinase ( SAPK)/ERK kinase 1, and MKK-4 stands for MAP kinase kinase 4 ] was activated in response to IL-6 and overexpression of dominant negative SEK-1/MKK-4 ( A-L ) reduced both IL-6 induced STAT3 Ser ( 727 ) phosphorylation as well as STAT3 transactivation
Song et al., Oncogene 2004 (Cell Transformation, Neoplastic) : Our results showed that mitogen activated protein kinase kinase 5 ( MEK5 ) was markedly induced ( more than 22-fold increase, P < 0.001 ) by Stat3-C expression