Gene interactions and pathways from curated databases and text-mining

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IL22 — MMP13

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Wahlgren et al., J Pathol 2001 (Bone Diseases...) : Phorbol-12-myristate-13-acetate, interleukin-6 , and tumour necrosis factor-alpha and heparin with the tumour promoter or cytokines potently enhanced ( up to nine-fold ) MMP-8 and -13 expression by the RPMI 8226 myeloma cell line, as evidenced by western blotting and semi-quantitative reverse transcriptase-polymerase chain reaction
Himeno et al., J Bone Miner Res 2002 (Ossification, Heterotopic) : In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1, platelet derived growth factor ( PDGF ), interleukin (IL)-1beta , and thyroid hormone ( T3 ) induced osteopontin and MMP-13 expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Im et al., J Biol Chem 2007 : bFGF stimulation of MMP-13 was mediated at the transcriptional level and, at least in part, by stimulation of interleukin-1 production
Ahmad et al., Cell Signal 2007 (MAP Kinase Signaling System) : MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1 induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation
Ito et al., Ultrasound Med Biol 2012 : Low-intensity pulsed ultrasound inhibits messenger RNA expression of matrix metalloproteinase-13 induced by interleukin-1ß in chondrocytes in an intensity dependent manner
Culley et al., Arthritis Rheum 2013 (Disease Models, Animal...) : Knockdown of each class I HDAC diminished interleukin-1 induced MMP13 expression